Kidney International® The ASCEND-NHQ Randomized Trial Found Positive Effects of Daprodustat on Hemoglobin and Quality of Life in Patients With Non-Dialysis Chronic Kidney Disease This clinical trial administered a daily daprodustat or a placebo pill to 614 patients with CKD and anemia for 28 weeks. People treated with daprodustat had a larger increase in hemoglobin and less...
Kidney International® Editorial Selection Perspectives on Early Detection of CKD: The Facts, the Questions, and a Proposed Framework for 2023 and Beyond To guide stakeholders on whether to establish early detection and intervention programs for CKD, an ISN working group examines whether the benefits of early-detection programs outweigh the cost and potential moral hazard. The authors encourage...
Watch the latest ISN video abstracts from the @ISNeducation Social Media Team. Watch the videos here. The videos are based on papers from Kidney International® and Kidney International Reports®: A Novel Direct Adenosine Monophosphate Kinase Activator Ameliorates Disease Progression in Preclinical Models of Autosomal Dominant Polycystic Kidney Disease Transitional B cell Cytokines Risk Stratify Early Borderline Rejection After Renal...
Kidney International Improving and Maintaining Quality of Hemodialysis in Areas Affected by War: A Call to Action In this “Nephrologists Sans Frontières” section of KI, Alasfar and colleagues discuss the long-term implications of the Syrian war on the delivery of renal replacement therapy in affected regions. They propose several strategies to manage the situation, including creativity in...
As the global burden of chronic kidney disease (CKD) rises, “Perspectives on Early Detection of CKD: The Facts, the Questions, and a Proposed Framework for 2023 and Beyond” presents timely information from ISN leaders on early CKD detection and a framework for adoption. Read the paper in Kidney International here. This paper culminates two years of work that...
Kidney International KDIGO Conference Report on Home Dialysis Controversies The Kidney Disease: Improving Global Outcomes (KDIGO) conference, held in May 2021, sought to address the global underutilization of home dialysis therapies and identify approaches and strategies to expand their use. The conference also addressed the financial implications of home dialysis and how best to improve the...
Watch the latest ISN video abstracts from the @ISNeducation Social Media Team here. The videos are based on papers from Kidney International and Kidney International Reports: Discovery of Seven Novel Putative Antigens in Membranous Nephropathy and Membranous Lupus Nephritis Identified by Mass Spectrometry Results From Part A of the Multi-center, Double-blind, Randomized, Placebo-Controlled NeflgArd Trial, Which Evaluated Targeted-release...
Read WCN'23 open-access abstracts here. The World Congress of Nephrology 2023 accepted abstracts have been published in the latest supplement to Kidney International Reports.
Kidney International P32: A Sex- and Gender-sensitive Model for Evidence-based Precision Medicine - From Knowledge Generation to Implementation in the Field of Kidney Transplantation. The authors propose a new evidence-based precision medicine framework – the P32 model, which considers individual sex- and gender-related domains and their intersection with ethnicity, geography, and other demographic and social variables. The model...
Kidney International Editorial Selection Endemic Rise in Cases of Acute Kidney Injury in Children in Indonesia and Gambia: What is the Likely Culprit and Why? This report sheds light on the sudden rise in acute kidney injury (AKI) cases in Indonesia and Gambia. The increase has been linked to poor quality control in manufacturing syrup medications...
Watch the latest ISN video abstract from the @ISNeducation Social Media Team. Watch the video here. This video is based on a paper from Kidney International Reports: Antibody Guided Therapy In PLA2R-associated Membranous Nephropathy
The ISN-KI Early-Career Researcher (ECR) Award recognizes outstanding research in basic and clinical science published in Kidney International (KI) in 2022. The ISN-KI Editorial Fellowship, designed for early-career kidney care professionals, provides training opportunities for reviewing and evaluating manuscripts and managing editorial responsibilities for a world-renowned nephrology journal. The Editorial Fellows will train with the...
Kidney International: Kidney Health for All: Preparedness for the Unexpected in Supporting the Vulnerable A special report from the World Kidney Day Joint Steering Committee presents an overview of the adverse effects of devastating events on the complex medical needs of those affected by kidney disease. The report highlights the increasing need to create resilient healthcare...
Kidney International: Results From Part A of the Multi-center, Double-blind, Randomized, Placebo-controlled Nefigard Trial, Which Evaluated Targeted-release Formulation of Budesonide for the Treatment of Primary Immunoglobulin A Nephropathy To verify the findings of the 2b NEFIGAN trial, the phase 3 NefigArd trial tested the efficacy and safety of nine months of treatment with Nefecon® versus placebo...
Home Dialysis: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference The level of home dialysis use worldwide is low despite its association with greater patient autonomy and treatment satisfaction compared with in-center modalities. In May 2021, KDIGO held a conference focusing on determining dialysis modality choice and distribution and strategies to expand home...
Kidney International: Glomerular Diseases in Pregnancy: Pragmatic Recommendations for Clinical Management Glomerular diseases are a frequent cause of chronic kidney disease in young women and generate many challenges in pregnancy. An international working group reviews current literature and expert opinions on glomerular diseases in pregnancy to provide practical information for nephrologists. The authors highlight areas of clinical...
Uncovering Risk Factors for Kidney Injury in Children With a Solitary Functioning Kidney A nationwide, multicenter study of children diagnosed with congenital or acquired solitary functioning kidney before adulthood indicates that a significant proportion will develop kidney injury over time, with kidney agenesis and being overweight as principal risk factors. Long-term Outcomes of Children and Adolescents...
Defining Measures of Kidney Function In Observational Studies Using Routine Health Care Data: Methodological and Reporting Considerations This review illustrates the diversity of working definitions of kidney disease in scientific literature and discusses the advantages and limitations of the most commonly used approaches. The authors summarize ways to identify and overcome possible biases and propose a framework...
Kidney International Particulate Matter of Air Pollution May Increase Risk of Kidney Failure in IgA Nephropathy. Environmental pollution has been associated with the progression of chronic kidney disease in the general population. This study specifically investigated the influence of exposure to fine particulate matter less than 2.5 μm in diameter (PM2.5) on IgAN progression. Kidney International Reports Leveraging...
ISN-KI Fellowships are non-funded positions designed for early-career professionals and academics working in nephrology, dialysis, and transplantation who are interested in learning editorial skills at Kidney International, one of the world's top journals in kidney care. Find out more and apply here. The closing date for expressions of interest is December 16, 2022. We asked current...