Research

Pin Your Trial Network on the ISN Network of Trials Networks Map!

The ISN-ACT (Advancing Clinical Trials) has created an online map tracking trial networks in kidney care research around the world. The aim is to facilitate clinical trial capacity and professional exchanges and collaboration by connecting people undertaking clinical trials and related studies in nephrology. The map allows researchers to quickly locate trial networks with the capacity...

International Practices and Challenges Surrounding COVID-19 Vaccination – Results From ISN Survey Published in BMJ Open

"Availability and Prioritization of COVID-19 Vaccines Among Patients With Chronic Kidney Disease and Kidney Transplant - A Global Survey by the International Society of Nephrology" has been published in BMJ Open. Read the manuscript here. The paper is based on a survey initiated by a team of ISN members on the availability, preparation and prioritization of...

ISN i3C Working Group Meeting on Intervention Strategies for Chronic Kidney Disease of Unknown Origin Generates Publication

The manuscript “Challenges and Opportunities in Interventions for Chronic Kidney Disease of Unknown Origin (CKDu): Report from the International Society of Nephrology Consortium of Collaborators on CKDu” has been published in Kidney International. Read the manuscript here. The paper was drafted after a special ISN i3C Working Group meeting was held to discuss potential interventions in communities...

Kidney International and Kidney International Reports Editorial Selections

Defining Measures of Kidney Function In Observational Studies Using Routine Health Care Data: Methodological and Reporting Considerations This review illustrates the diversity of working definitions of kidney disease in scientific literature and discusses the advantages and limitations of the most commonly used approaches. The authors summarize ways to identify and overcome possible biases and propose a framework...

Apply to the ISN Clinical Research Program (CRP) – Get Help With Your Application From ISN CRP Chairs at 9 a.m. CET on January 10

The ISN Clinical Research Program (CRP) offers grants to researchers in low, lower-middle, and upper-middle-income countries to support research projects on detecting and managing noncommunicable chronic diseases such as CKD, AKI, hypertension, diabetes, and cardiovascular disease. Apply to the program here. Regional coordinators must receive the application by April 1. Final applications are accepted once per...

Access ISN-ACT Webinar on Hypoxia-inducible Factor-prolyl Hydroxylase Inhibitors

Did you miss the live session? A recording is available here. Professor Meg Jardine, ISN-ACT (Advancing Clinical Trials) Committee chair, and speakers David Wheeler, Jonathan Barratt and Jodie Babitt joined in a lively discussion on this treatment option and on the management of anemia in CKD patients. This webinar is supported by Astellas.

Join Us in Congratulating Four New ISN-Named Fellows  

Clockwise, from top left: Carinna Hockham, Anastasiia Zykova, Suman Behera and Mark Canney The ISN Executive Committee and Council have approved four “ISN-Named Fellows.” Please join us in congratulating Suman Behera from ISN I3C (CKDu), Mark Canney from ISN iNET-CKD (cohort studies), and Anastasiia Zykova and Carinna Hockham from ISN-ACT (clinical trials). Get to know our new ISN-Named Fellows here. These early-career ISN...

Latest Kidney International and Kidney International Reports Editorial Selections

Kidney International Particulate Matter of Air Pollution May Increase Risk of Kidney Failure in IgA Nephropathy. Environmental pollution has been associated with the progression of chronic kidney disease in the general population. This study specifically investigated the influence of exposure to fine particulate matter less than 2.5 μm in diameter (PM2.5) on IgAN progression. Kidney International Reports Leveraging...

Publishing and Reporting a Trial: Take a Look at the Latest Narrative-based Chapter of the ISN-ACT Clinical Trials Toolkit

The sixth narrative-based chapter of the Clinical Trials (ISN-ACT) Toolkit describes best practices when writing a scientific paper to boost the impact of your published study. Discover chapter 6 here alongside previous chapters. This series of narratives is produced by the ISN-ACT Clinical Trials Toolkit subgroup members based on topics from the ISN-ACT Clinical Trials Toolkit,...

Discover the Latest Video Abstracts

Watch the latest ISN video abstracts from the @ISNeducation Social Media Team on inhibiting inflammation with anti-cytokine therapy and post-dilution hemodiafiltration. Watch the videos here The videos are based on papers from Kidney International and Kidney International Reports: A Randomized Controlled Pilot Trial of Anakinra for Hemodialysis Inflammation High-volume Hemodiafiltration and Cool Hemodialysis Have a Beneficial Effect on Intradialytic...

Listen to the ISN GTF Twitter Space Recording on the TESTING Randomized Clinical Trial on Oral Methylprednisolone

The first ISN Global Trials Focus (GTF) Twitter Space took place on November 17, 2022. The interactive live audio discussion focused on the GTF project and the TESTING (Therapeutic Evaluation of Steroids in IgA Nephropathy Global) randomized clinical trial on oral methylprednisolone. Access the Twitter Space conversation here.      The event generated much interest, with...

Take Part in the ISN GTF Twitter Space to Discuss the TESTING Randomized Clinical Trial on Oral Methylprednisolone

  Join the ISN Global Trials Focus (GTF) editorial team and researchers from the TESTING* study for a live audio discussion on the GTF project and the TESTING randomized clinical trial on oral methylprednisolone. Access the Twitter Space conversation here on November 17, 2022, at 10 p.m. CET. Scan the QR code in the image above to...

What Is the Kidney Function of Workers Exposed to Heat Stress After a Two-year Follow-up?

The paper "Kidney Function in Factory Workers Exposed to Heat Stress - a 2-year Follow-up Study" by Fabiana Nerbass has been published in the Journal of Occupational of Environmental Medicine. Read the article here.  The research highlights the value of collaboration among investigators, organizations and communities. Fabiana Nerbass, from Fundação Pró-Rim in Joinville, Brazil, received the...

Join the first ISN Global Trials Focus Twitter Space to Discuss the TESTING Randomized Clinical Trial on Oral Methylprednisolone

The first ISN Global Trials Focus (GTF) Twitter Space will be held on November 17, 2022, at 10 p.m. CET. The live audio discussion will address the GTF initiative and the Therapeutic Evaluation of Steroids in IgA Nephropathy Global (TESTING) Randomized Clinical Trial, “Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in...

The ISN Holds First Consensus Meeting on Guidance for Optimal Pre-clinical Animal Studies in Translational Nephrology (TRANSFORM)

The ISN’s TRANSFORM meeting (TRAnslational Nephrology Science FOR new Medications) took place in Brussels, Belgium, from October 8-9, 2022. The meeting gathered patients, clinical and academic researchers, regulators, and industry partners to: Report ISN Research Working Group activities describing the current landscape and future possibilities. Reach consensus on guidance that optimizes animal study design and drives the...

How Do You Measure Community Engagement in Kidney Research? Find Out From an ISN Hydration and Kidney Health Investigator

The paper “Community Engagement in Kidney Research: Guatemalan Experience" by Angie Aguilar-González was recently published in BMC Nephrology. Read the article here. The research highlights the value of collaborative research between investigators, organizations and communities. Angie Aguilar-González, from FUNDANIER (Fundación para el Niño Enfermo Renal) in Guatemala City, Guatemala, received the 2018 'Hydration and Kidney Health...

Tune in for Talks by ISN-KI Early-Career Researcher at Upcoming Oncology-Nephrology Meetings

Naoka Murakami, 2022 ISN-KI Early-Career Research Award winner, will present at two upcoming oncology-nephrology meetings. The Onco-Nephrology Symposium, 2022, will take place in hybrid format on September 30 in Boston, USA. The event offers up-to-date information and insights from national and international experts in this constantly evolving subspecialty. Join Naoka Murakami for 'Immune Checkpoint Inhibitors and...

Join the Live #NephTrials Discussion on Efficiency in Clinical Trials: ‘Getting to the H4RT of Registry Design’ on September 29

Connect with Fergus Caskey, Roberto Pecoits-Filho, Michael Walsh, Joel Topf, Manasi Bapat, and Swapnil Hiremath at the latest #NephTrials discussion on September 29, 2022, at 1 p.m. CEST. Why do we need more efficient clinical trials? What is a registry and why are registries useful? What is a registry-based randomized controlled trial, and how does...

New! Latest Narrative-based Chapter of the ISN-ACT Clinical Trials Toolkit On Building a Statistical Analytical Plan – Out Now

Are you planning a research project but need help with statistics? Access the new chapter here. This narrative-based chapter of the Clinical Trials (ISN-ACT) Toolkit guides you through key statistical concepts to help you identify variables and use a design study best suited to the data type and target population. The fictional narrative addresses: Descriptive and inferential statistics Primary...

Building a Statistical Analytical Plan: Look Out for the Next Narrative-based Chapter of the ISN-ACT Clinical Trials Toolkit

The upcoming narrative-based chapter of the Clinical Trials (ISN-ACT) Toolkit will describe descriptive and inferential statistics to help you easily get to grips with building a statistical analytical plan.  The new chapter will be released in July 2022.  This series of narratives is produced by ISN-ACT Clinical Trials Toolkit subgroup members based on topics from the ISN-ACT...