Research

ISN International Consortium CKDu Collaborators (ISN i3C) Network Meeting Affirms Need to Build Capacity for Kidney Biopsies in CKDu Within Ethical Framework

Held in May, the meeting brought together 40 members of the ISN i3C (International Consortium CKDu Collaborators) network and the ISN Renal Pathology Working Group The meeting highlighted the need to increase kidney biopsies in CKDu (chronic kidney disease of unknown origin) and improve biopsy preservation.  Three ISN i3C network members presented: Richard Johnson outlined the usefulness of kidney...

Discover Highlights from a Successful First iNET-CKD Webinar on Building a Cohort Study

Would you like to understand the key design elements of a cohort study and learn how to draft a study protocol? Watch the first iNET-CKD webinar, "Building a Cohort Study: Insight from Investigators," here. More than 200 people attended the webinar on May 10, generating a lively conversation on Twitter: Access the thread here. Participants came...

Are You Involved in CKDu Research? Explore Ongoing Studies and Share Your Data on the ISN Observatory of CKDu 

The ISN Observatory of CKDu is a catalog where researchers can submit their findings or view other studies. This system facilitates global collaboration and data exchange, enabling researchers to know what studies are ongoing at any given time. The initiative was developed by the ISN i3C (International Consortium CKDu Collaborators) working group as part of...

How Technology and Communication are Transforming Kidney Care: Read the Paper on eHealth in the BMJ

"Global Status of Infrastructure and Opportunities for eHealth: Implications for Kidney Care Delivery in Low Income and Lower-middle Income Countries" has been published in the BMJ. Read the paper here. The paper describes the status of eHealth services and infrastructures across the ten ISN regions, using data from the World Health Organization's (WHO) third global survey...

Trial Registration and Ethics: Read the Latest Chapter of the ISN-ACT Narrative-based Clinical Trials Toolkit

Chapter four of the Narrative-based Clinical Trials (ISN-ACT) Toolkit highlights the required ethical, practical, and legal issues a researcher must address before carrying out a clinical study. Access the latest chapter here. A fictional group of nephrologists enrolled in the ISN Emerging Leaders Program, setting up an international multicentric study provides the backdrop to examine concepts...

Watch the ISN Webinar on Challenges and Opportunities for Interventions in CKDu

More than 100 people attended the ISN webinar "Challenges and Opportunities for Interventions in CKDu" organized by the ISN i3C (International Consortium CKDu Collaborators) Network on February 17, 2022. Moderated by Shuchi Anand, the webinar focused on the need for interventions to benefit patients and communities affected by chronic kidney disease of Are you interested in...

Newly Revised ISN-ACT Clinical Trials Toolkit Available to Explore Now

Explore the second revised edition of the ISN-ACT Clinical Trials Toolkit here.  The online Clinical Trials Toolkit was first launched in 2020 to provide the kidney community with a central and user-friendly resource for those wishing to participate in randomized research. Watch a short introductory video on the toolkit here. Listen to a podcast on the toolkit here (episode...

Do You Follow the Monthly ISN-ACT Global Trials Focus List? Discover it Now and Welcome Its New Leadership 

The ISN-ACT Global Trials Focus (GTF) is a monthly list identifying and summarizing recent interesting trials relevant to kidney disease.   The GTF is promoted and published on the ISN website, the ISN Academy, the ISN Insight newsletter, and ISN social media channels. The monthly summary is also discussed during #NephTrials, a series of conversations on...

New Research Paper Highlights Significance of CKD as a Public Health Problem 

The paper "Mortality and Resource Use Among Individuals with Chronic Kidney Disease or Cancer in Alberta, Canada, 2004-2015" was published in JAMA Network Open on January 25.  Read the paper here.  The research for the paper was led by Marcello Tonelli, iNET-CKD, i3C, and ISN-ACT Networks member. Aiming to support chronic kidney disease (CKD) advocacy efforts,...

Discover the Findings of the “Global Survey of Kidney Nutrition”

The paper, “Assessing Global Kidney Nutrition Care,” has been published in the Clinical Journal of the American Society of Nephrology. Read the paper here. The ISN Global Kidney Health Atlas Committee partnered with the International Society of Renal Nutrition and Metabolism to develop a Global Kidney Nutrition Care Atlas. 155 ISN-affiliated countries completed an electronic survey evaluating...

Coming Soon – Chapter Four of the ISN-ACT Narrative-Based Clinical Trials Toolkit

Chapter four of the Narrative-Based Clinical Trials (ISN-ACT) Toolkit will highlight the many ethical, practical, and legal issues that researchers need to address before starting a clinical study. The ISN-ACT Clinical Trials Toolkit subgroup members are producing this series of stories, based on topics from the ISN-ACT Clinical Trials Toolkit, to facilitate understanding of clinical trial methodologies. Get involved in ISN's...

Discover the Protocol for a Scoping Review on Early CKD Identification

Over the past several months, a group of ISN members has collaborated on a project to provide a shared understanding of the inherent opportunities and challenges of implementing early CKD identification and intervention programs. A component of this initiative, a protocol for a scoping review, has just been published here. The review aims to synthesize available...

Announcing the Winners of the ISN-KI Early-Career Researcher Awards

The ISN-KI Early-career Researcher Award recognizes outstanding research in basic and clinical science published in Kidney International (KI) in 2020 and 2021. Please join us in congratulating:  Basic Science winners Idris Boudhabhay (France) Complement Activation Is a Crucial Driver of Acute Kidney Injury in Rhabdomyolysis Jihyun Yang (Korea) Intestinal Microbiota Controls Acute Kidney Injury Severity by Immune Modulation Clinical Science winners Naoka...

Global Survey of Kidney Nutrition Reveals Shortage of Qualified Dieticians

The paper, “Assessing Global Kidney Nutrition Care,” will shortly be published in the Clinical Journal of the American Society of Nephrology. The International Society of Nephrology (ISN) Global Kidney Health Atlas (GKHA) Committee partnered with the International Society of Renal Nutrition and Metabolism (ISRNM) to develop a Global Kidney Nutrition Care Atlas. 155 ISN-affiliated countries completed...

More than 1,100 Participants Connect Online for MRAs and DKD Management Webinar Series

More than 1,100 participants from 107 countries joined the ISN webinar series on mineralocorticoid receptor antagonists (MRAs) and diabetic kidney disease (DKD) management held in October. The use of MRAs in DKD has historically been limited by its adverse side effects. This webinar series highlighted new developments in a rapidly evolving field, presenting the outcomes...

Last Chance to Submit a Research Article for a KI-ISN Early-Career Researcher Award Before Tomorrow’s Deadline

Submit your application here. The winners of these awards (two basic and two clinical science publications) will receive 500 USD each and be invited to present their papers at the 2022 World Congress of Nephrology. Discover the 2019/2020 winners and their research papers here. Find out more about the award and how to apply here.

Past ISN Fellows Contribute to New Research Article on Kidney Transplantation in LMICs

Five former ISN Fellows have collaborated with ISN member Mohamed Elrggal on the paper “Disparities in Access to Kidney Transplantation in Developing Countries,” now published in the journal Transplantation. Sibel Bek, Ali Shendi, Elliot Tannor, Yannick Nlandu, and Abduzhappar Gaipov contributed to the article, which examines factors implicated in deficiencies in kidney replacement therapy...

New Paper on Global Transplantation Capacity Published Using ISN Global Kidney Health Atlas Survey Results

"Global Estimates of Capacity for Kidney Transplantation in World Countries and Regions" is available as a domain paper on the (ISN-GKHA) web page. Access the paper here. The paper reports on findings from the 2018 ISN GKHA survey on the availability and affordability of quality kidney transplantation across countries and regions. The ISN Global Kidney Health Atlas...

Read Chapter Three of the ISN-ACT Narrative-Based Clinical Trials Toolkit on Participating as a Trial Site

The ISN-ACT Clinical Trials Toolkit subgroup members are producing a series of stories based on ISN-ACT Clinical Trials Toolkit topics to facilitate understanding of key clinical trial methodologies. The third chapter of the Narrative-Based Clinical Trials (ISN-ACT) Toolkit uses a fictional clinical discussion to show what it takes to become a trial site using a fictional clinical discussion. A...

New Global Collaboration to Accelerate Treatments for Kidney Disease 

The ISN and the George Institute for Global Health have signed a Memorandum of Understanding (MOU) to develop a network of patients with kidney disease willing to participate in clinical research projects, accessible through a single global CKD platform. The aim of the Global Kidney Patient Trials Network (GKPTN) is to accelerate the development...