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ISN-H4KH Grant Awardee’s Research Findings Published

“Water intake and progression of chronic kidney disease: the CKD-REIN cohort study” by ISN Hydration For Kidney Health (ISN-H4KH) Research Grant awardee, Sandra Wagner, was published in Nephrology Dialysis Transplantation on February 12, 2021.

Read the full article here.

Sandra Wagner et al. investigated the relationship between water intake and kidney failure progression in CKD patients participating in the CKD-REIN prospective cohort study.

Patients were evaluated daily water intake and daily urine volume. The effect of the decreasing urine-concentrating ability related to kidney function decline was also studied.

The study suggests an optimum range of 1 to 2 L/day water intake for CKD patients, which should be confirmed in other cohorts or clinical trials. Until new guidelines review evidence on hydration tailored for CKD patients, this range may be recommended, with adjustments according to thirst and excretion.

In 2018, Sandra Wagner, from France, received an ISN Research Grant, with support from Danone Nutricia Research, for her project: “Association of water intake with osmolarity and renal outcome in patients with CKD stage 3-4. The French CKD-REIN Cohort study.”

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