Every month the ISN-ACT Team lists interesting new randomized controlled trials (RCTs) from around the world. Highlight: SGLT-2 inhibition strikes again Dapagliflozin in Patients with Chronic Kidney Disease See the latest trials here. A summary of the highlighted trial is now available in French, Mandarin, and Spanish. Support equal access to nephrology research: Become an ISN Member!
The ISN i3C (International Consortium CKDu Collaborators) group developed the ISN Observatory of CKDu as part of its Collaboration Plan with the World Health Organization (WHO) to facilitate information exchange and raise awareness of the urgent issue of Chronic Kidney Disease of unknown etiology. Collating ongoing studies and efforts on CKDu provides a valuable overview...
Every month the ISN-ACT Team lists interesting new randomized controlled trials (RCTs) from around the world. Highlight: LOL-HD study: Laughter therapy may reduce depressive symptoms in hemodialysis patients See the latest trials here. A summary of the highlighted trial is now available in French, Spanish, and Mandarin. Support equal access to nephrology research: Become an ISN Member!
The webinar, Gathering Wisdom: SGLT2i in Diabetic and Non-Diabetic Kidney Diseases, will be held on November 9, 2020, at 3 p.m. CET. This symposium will focus on the current state of therapeutic options for CKD and DKD, with specific attention to accumulating evidence of recent SGLT2i trials. The webinar is supported by an unrestricted educational grant by AstraZeneca. Registration details will follow shortly.
The ISN-ACT Clinical Trials Toolkit is an open-access, online resource to assist trial design, study conduct, data management, data analysis, and publication. More than ever, clinical trials in nephrology are needed to generate high-quality evidence to inform all aspects of care for patients with or at risk of kidney disease, including those affected by COVID-19. Access...
Every month the ISN-ACT Team lists interesting new randomized controlled trials from around the world. Highlight: Diltiazem may be superior to nifedipine for post-partum hypertension in pregnancy. See the latest trials here. From October 2020, the GTF will be available in French, Spanish, Arabic, and Mandarin. Would you like to support equal access to nephrology research? Become an ISN...
Dr. Rolando Claure Del Granado and colleagues involved in the ISN 0by25 initiative in Bolivia Every year, the Scientific Committee of the Medical College of Bolivia awards outstanding studies and investigators that significantly impact the local population. This year, the jury recognized the academic and research activities of Dr. Rolando Claure Del Granado and selected the...
The ISN-ACT Global Trials Focus team has collected and published a new list of randomized research from nephrologists around the world for August 2020. Each trial is reviewed in context and the risk of bias in seven key areas is assessed. Highlight: Allopurinol does not slow the progression of chronic kidney disease in patients with type 1...
The full DAPA-CKD trial results will be presented and reviewed at the ESC Congress 2020, Sunday, August 30, 17:00 – 17:30 CET. Topic Renal failure and Cardiovascular Disease Chairpersons Rory Collins (Oxford, UK); Frank Ruschitzka (Zurich, Switzerland) Presentations: DAPA-CKD – Dapagliflozin in Patients with CKD: Hiddo Heerspink (Groningen, Netherlands) DAPA- CKD – Live Prime Discussion: Diederick E Grobbee (Utrecht, Netherlands) Q&A Session The...
The ISN invites nephrologists to register patients affected by COVID-19 on the new global COVID registry. The ISN collaborated with the University of Cambridge to develop CORONATION, the Coronavirus multinational observational registry, a data entry portal accessible to nephrologists worldwide to collect anonymous data on individual people with kidney disease and the COVID-19 infection. For more information, please visit...
Kidney International will shortly publish the International Consensus Definitions of Clinical Trial Outcomes for Kidney Failure: 2020, developed from the 1st International Consensus Meeting on Defining Kidney Failure in Clinical Trials hosted by the ISN in Vancouver, BC, Canada, in early 2020. This is the first attempt by the international nephrology community to identify reproducible,...
Every month the ISN-ACT Team lists interesting new randomized controlled trials from around the world. Highlight: Early ACE-inhibition is safe in pediatric Alport’s Syndrome and may be effective See the latest trials here
The International Society of Nephrology urges all investigators and industry partners to include people with kidney diseases in research activities related to COVID-19. The ISN-ACT (Advancing Clinical Trials) Committee has released a statement on the urgent need to include patients with kidney diseases in clinical trials related to COVID-19. Despite preliminary studies demonstrating the increased risk...
Find key results from your region through scorecards. Available here Share the results from your region via social media or other media and press channels to support discussions on and advocate for kidney health care.
Over 5,000 people worldwide have already visited ISN's recently launched, open-access, online resource to assist you in trial design, study conduct, data management, data analysis, and publication. More than ever, clinical trials in nephrology are needed to generate high-quality evidence to inform all aspects of care for patients with or at risk of kidney disease,...
In collaboration with the World Health Organization (WHO), the ISN i3C (International Consortium CKDu Collaborators) group has developed the ISN Observatory of CKDu to facilitate the exchange of information and knowledge to raise awareness of the urgent issue of Chronic Kidney Disease of unknown etiology. The input of experts in the field of CKDu provides both the ISN...
As part of its Collaboration Plan with the World Health Organization (WHO), the ISN i3C (International Consortium CKDu Collaborators) group has developed a CKDu Observatory Map to facilitate the exchange of information and knowledge in order to raise awareness of the urgent issue of Chronic Kidney Disease of unknown etiology. Be the first to access...
The ISN Global Kidney Health Atlas team has prepared summary slides of the ISN GKHA 2019 focusing on each ISN region individually. ISN invites members to share the results from their region with colleagues and key stakeholders to support discussions on and advocate for kidney health care with relevant national and regional health/policy/education officials. The new material contains...
Every month the ISN-ACT Team lists interesting new randomized controlled trials from around the world. Highlights: Keeping it simple with restriction: fluid restriction as good as diuretics and oral salt for SIAD Deciding HDF or HD: nothing to lose sleep over See the latest trials here.
“High water intake and low urine osmolality are associated with favorable metabolic profile at a population level: low vasopressin secretion as a possible explanation” by ISN Hydration For Kidney Health (ISN-H4KH) Research Grant awardee, Sofia Enhörning, was published in the European Journal of Nutrition in February. Sofia Enhörning et al, investigated if low total water intake or high...